Congenital pulmonary lymphangiectasia: an unusual presentation of nonimmune hydrops in a preterm infant.

June 2012

Mele P, Sridhar S.

Source

Division of Neonatology, Department of Pediatrics, Stony Brook Long Island Children's Hospital, New York 11794, USA. Patricia.Mele@sbumed.org

Abstract

Congenital pulmonary lymphangiectasia (CPL) is a rare developmental disorder of the lung. CPL can present antenatally as nonimmune hydrops with pleural effusions, which are frequently associated with polyhydraminos. CPL presents in the neonatal period with severe respiratory distress and can be complicated by chylothorax. Diagnosis is difficult, as radiographic findings are nonspecific. Lung biopsy is indicated in some severe cases to diagnose CPL. The majority of infants with this condition rarely survive the neonatal period and are often diagnosed at autopsy. The final diagnosis is confirmed histologically by lung biopsy or at postmortem. We report a rare case of CPL in a preterm female infant presenting with severe nonimmune Hydrops fetalis who survived the neonatal period, and report clinical follow-up to early childhood.

Lippincott, Williams, Wilkins

Conjunctival Lymphangiectasia Presenting as Pediatric Pseudopterygium.

June 2012

Pastora N, Peralta-Calvo J, Yebenes-Gregorio L, Abelairas J, Hierro-Zarzuelo A.

Source

Ophthalmology Department (N.P., J.P.C., J.A., A.H.Z.), Hospital Universitario La Paz, Madrid, Spain Pathology Department (L.Y.G), Hospital Universitario La Paz, Madrid, Spain.

Abstract

OBJECTIVES:

The aim of this study is to report a case of conjunctival lymphangiectasia simulating a pediatric pterygium.

METHODS:

A 10-year-old girl with Turner syndrome and familial history of pterygia presented because of a conjunctival growing lesion clinically consistent with pterygium in her left eye. Visual acuity (VA) was 20/20 in the right eye and 20/40 in the left eye. Cycloplegic refraction was +1.50sph -0.50cyl×93° and +9.00sph -9.00cyl×180° in the right and left eyes, respectively.

RESULTS:

Resection of the lesion with amniotic membrane implantation and conjunctival autograft was performed. The histologic examination revealed conjunctival lymphangiectasia. Ten months later, the patient did not show any signs of recurrence. Refraction in the left eye was +0.5sph -1.5cyl×70°, and spontaneous VA was 20/20 in both eyes.

CONCLUSIONS:

Pediatric pseudopterygium may be the clinical presentation of several ocular surface disorders. Thus, pathologic analysis of this lesion should be considered to determine its exact nature. Surgery lessens the refractive defect and hastens visual recovery.

Lippincott, Williams & Wilkins

Segmentation of Crohn, Lymphangiectasia, Xanthoma, Lymphoid Hyperplasia and Stenosis diseases in WCE.

2012

Hajo-Maghsoudi O, Talebpour A, Soltanian-Zadeh H, Haji-Maghsoodi N.

Source

Department of Radiation Medicine, Beheshti University of Tehran, Tehran, Iran.

Abstract

Wireless capsule endoscopy (WCE) is a great breakthrough for Gastrointestinal (GI) Tract diagnoses which can view the entire gastrointestinal tract, especially the small bowel, without invasiveness and sedation. However, a tough problem associated with this new device is that too many images to be inspected by naked eyes is difficult for physicians, Thus it is essential to find an automatic and intelligent diagnosis method to help physicians. In this paper, a new segmentation algorithm for detection of Lymphangiectasia, Xanthoma, Crohn, and Stenosis in WCE images is proposed. This new approach mainly uses the HSV color space, sigmoid function and canny edge detector. We compare our method with a fuzzy c-mean clustering. We show that sensitivities of the sigmoid function for Lymphangiectasia, Lymphoid hyperplasia, severe Crohn's disease, Xanthoma and ulcerated Stenosis are respectively 89.32%, 91.27%, 95.45%, 87.01%, 97% and sensitivities of the fuzzy c-means clustering with same order are 83.91%, 86.7%, 96.38%, 90.4%, 93.83%. Totally, the sigmoid function is more specific and sensitive, with same accuracy.

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